Bionic Pancreas… iLet… A "Cure" By Any Other Name…

i1The team from Bionic Pancreas is asking everyone to spread the news… and I’m happy to do so.

I believe in the work they are doing and they are the horse (OK, the artificial pancreas system) I am backing until there is a biological cure. I know my body and I know that I need the glucagon portion of this system to keep my blood glucose levels in range.

I’ve donated before and I will again to this…And I’d love for you to read on and hear what they’re doing. We’re so close. And you can help.

From The Bionic Pancreas Team:

Exciting innovative work is being done at Boston University that is focused on profoundly improving outcomes in type 1 diabetes and substantially reducing the burden of diabetes management. Ed Damiano and his team have developed the one and only fully integrated, fully automated bihormonal bionic pancreas. They have done so in large part from charitable donations from the type 1 community. I support this project.

I am asking for your help. I invite you to look at the work that they have done, the results of multiple outpatient trials that they have completed with their clinical collaborators across the US, and the iLetTM, which was unveiled in July 2015 at the Friends for Life Children with Diabetes Conference in Orlando, Florida.

Ed and his team need our help to bring this to children and adults living with type 1 diabetes. After looking at this information, I am asking you to donate to this project.

Boston University is a 501(c)(3) organization, so your donation is tax deductible. Boston University assesses no overhead on your gift, so 100% of your donation goes directly to a dedicated account set aside for the Bionic Pancreas Project.

Without our help, this project may encounter a delay from their goal of conducting the final pivotal trial in 2017. These are the trials needed in order to submit the device for final FDA approval.

While Ed’s group has received funding from the NIH, the Helmsley Charitable Trust, and the JDRF, this money has funded the clinical studies, not the development of the device itself. The project needs at ~ $1.5 million this year in order for his team to remain on track with their device development efforts.

I have included some information from their website as well as links to more information. I have also included a pledge form. If you need more information or have any questions, please feel free to reach out to me or Scott Scolnick on the Bionic Pancreas fundraising team.

His contact information is Scott Scolnick, M.Ed., sscolnic@bu.edu, 617-608-7362.

Thank you in advance for your support.

Introducing the iLet

slant_view_200x422We’ve taken a big step towards a marketable Bionic Pancreas – the iLet.

Built-in wireless CGM technology

Using Dexcom CGM technology, the iLet offers its own, built-in, continuous glucose monitor. All that is required is a Dexcom sensor and transmitter and the iLet will replace your regular CGM receiver.

No separate processor, all the smarts are already built-in.

No longer do we need a laptop or an iPhone to run our insulin and glucagon dosing algorithms; the iLet brings with it a dedicated platform to run all of our dosing algorithms on a single, handheld device.

The iLet is an automated, personalized diabetes management platform that automatically learns your insulin requirements and automatically adapts its insulin dosing to your ever- changing needs, allowing you to focus on the rest of your life.

Two pumps in one

cartridges_550x245The iLet integrates two independent pumping systems, one for insulin and one for glucagon. These pumps are automatically commanded by our insulin and glucagon dosing algorithms every 5 minutes.

Streamlined, simple, and friendly user-interface

A touch-screen display brings all the information you need right to your fingertips through an extremely simple and elegant user-interface.

NOTE: The iLet is an investigational device and is not yet FDA approved. Our goal is to conduct human factors studies and begin clinical trials testing the iLet in 2016.

Donations support the Bionic Pancreas Project at Boston University. 100% of your gift is tax deductible, and goes directly to the work being done on the one and only fully integrated, fully automated bihormonal bionic pancreas.

 

7 comments
  1. Person with type-1 here. Excellent technology but a few questions:
    1) I presume you’re using conventional (non-first-phase) insulin such as novolog or apidra, but nothing “exotic”? Given that the peak times for those insulins is maybe 90 minutes, it’s still a blunt instrument you’re working with. Curious how you work around those limitations…

    2) if I trusted my life to what my Dexcom CGM thought my BG was, I’d be dead in a week. It’s pretty good, so no criticism implied of Dexcom here, but not nearly good enough as a sole source of truth. How do you work around this?

    What are the mg/dl numbers for your target range in the presentation (your green zone) — curious how tight you can go.

    Thanks — exciting stuff!

    Cheers,
    Jason

  2. Please send me any and all updates on new technology results regarding Type 1 Diabetes

  3. It’s great to see that other organizations/companies besides Pancreum (www.pancreum.com) are also working on a dual-hormone (insulin & glucagon) bionic (a.k.a. artificial) pancreas.

  4. I attended a fundraiser in Atlanta where Ed and Scott presented this amazing device. Based on the number of clinical trials they have successfully completed and the advanced development stage (and the fact that it is university/501c3 based), I’m left wondering why JDRF is not supporting them anymore? Why is JDRF’s Aaron Kowalski actively promoting the UVA insulin only artificial pancreas instead? Would appreciate your insight

  5. “A cure by any other name”? Really? It’s an improvement, sure. It’s far from a cure. If I have something sticking on my body that can potentially be ripped off, it is not remotely close to a cure.

    1. Elise,
      Thanks for your response! As many have said, there is no replacement for a biological cure. Until there is, this is as close as I will get to having a “functional” cure which allows me to have a better quality of life, not think quite so much about my blood glucose levels, and sleep well at night. I want normal blood sugars, which will help keep my body in shape until a biological cure is found. We all have different ideas of what the word “cure” means with Type 1 diabetes. For me, it’s this.

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